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Mark Louis Wess, MD

Mark Louis Wess, MD
4.83 out of 5 stars
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CenterWell Powdersville

3516 SC Hwy. 153
3516 SC Hwy. 153
Greenville, SC 29611
Greenville SC 29611

Education

University Of Cincinnati College Of Medicine

Languages spoken

English

Board certifications

American Board of Internal Medicine 1992

NPI

1861440042
Dr. Mark Wess, a board-certified internal medicine specialist, earned his medical degree from the University of Cincinnati College of Medicine, a Master of Science in Clinical Epidemiology from Harvard School of Public Health, and a B.S. in Pre-med and Chemistry from Xavier University. Dr. Wess has held esteemed academic appointments, including as a clinical instructor at the University of South Carolina School of Medicine Greenville, clinical associate professor at Clemson University, and associate professor at the University of Cincinnati. He brings a wealth of experience after working with MDLIVE as an urgent care virtual physician and serving as the SVP and chief information and analytics officer at Glidenet Healthcare. His tenure at Prisma Health saw him in pivotal roles as VP, Chief Health Information Executive, and Chief Medical Information Officer at Greenville Health System. Passionate about diabetes, heart health, and preventive care, Dr. Wess is committed to enhancing patient outcomes and improve healthcare delivery systems through his chosen path in medicine. In his free time, he enjoys the outdoors and making memories with his family.

Patient satisfaction ratings and comments

4.83 out of 5 stars
72 Comments
Aug 31, 2026
I had a great interaction with Dr Wess. All my concerns were discussed
Aug 31, 2026
I feel like the Dr. should look at all my medical conditions and MRI's and understand why I am on all my meds. My spine condition is not listed on my list of medical records and the reason I am on Tramadol seems to be a problem for my Dr

Provider numbers for agent use

  • Aetna: 4317721
  • Blue Cross and Blue Shield: 1861440042
  • DeVoted: LX468J-AB
  • Healthspring: 1861440042
  • Humana: 476411
  • Medicaid: 351559
  • Medicare Railroad: Q00728371
  • Medicare: SC0172L064
  • United Healthcare: 00040202356
  • United Healthcare: 00040667579
  • Wellcare: 4028105

Provider NPI

1861440042

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